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'Major Advance' in HIV Gene Therapy
Topic Started: Feb 20 2010, 10:06 PM (102 Views)
MorningMist
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'Major Advance' in HIV Gene Therapy
Study Shows HIV Gene Therapy Is Safe, Could Make Body Resist AIDS Virus
By Daniel J. DeNoon
WebMD Health News
Reviewed by Louise Chang, MD
Feb. 16, 2009 -- A one-time gene therapy that puts an anti- HIV RNA weapon into blood cells is safe and, in higher doses and stronger form, could make the body resist the AIDS virus, a clinical trial suggests.
This "major advance in the field" is the largest clinical trial ever to test genetically altered cells in humans, say UCLA researcher Ronald T. Mitsuyasu, MD, and colleagues.
"This study indicates that cell-delivered gene transfer is safe and biologically active in individuals with HIV and can be developed as a conventional therapeutic product," the researchers report in the Feb. 15 advance online issue of Nature Medicine.


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